Understanding Premature Ovarian Failure (POF or POI): Definition: POI is a condition where the ovaries cease to function properly before age 40, resulting in reduced estrogen production and infrequent or absent ovulation Infertility: POF significantly impacts fertility due to the ovaries' inability to produce eggs and hormones needed for conception. Symptoms: Besides irregular periods and infertility, women with POF may experience symptoms similar to menopause, such as hot flashes, vaginal dryness, and mood changes. Causes: While the cause is often unknown, potential factors include genetics (like Turner syndrome or Fragile X premutations), autoimmune diseases, and treatments like chemotherapy or radiation. Diagnosis: Diagnosis typically involves assessing menstrual history, hormone levels (particularly FSH), and sometimes ovarian ultrasound. Not Premature Menopause: POF is distinct from premature menopause. Women with POF may still have some ovarian function and potentially natural pregnancies, while menopause is a permanent cessation of menstruation. Psychological Impact: The diagnosis of POF can be emotionally challenging, impacting a woman's self-esteem and future plans. Ongoing Monitoring: Women with POF require regular monitoring for associated health issues, such as osteoporosis and cardiovascular disease. #gynaecologist #fertilitydoctor #nashik