Later Life Hormone Therapy Separating Fact from Fiction There's no upper age limit for HRT when prescribed safely. If you continue to benefit and risks are minimal , you can stay on it indefinitely. Annual reviews are key to ensure safety and ongoing benefit. Understanding the Risks • Transdermal estrogen patch or gel or spray with micronised progesterone has no added clotting risk. • Oral estrogen increases VTE risk , transdermal does not. • Breast cancer risk comes mainly from synthetic progestogens, not estrogen. • Micronised progesterone has a lower or no significant breast cancer risk. Bone, Heart & Longevity • Low-dose estrogen helps maintain bone strength and reduces fracture risk. • HRT remains first-line for preventing and treating osteoporosis in women 50 to 60, and beneficial even after 60 with individual assessment. • With well managed heart risk factors, CVD is not a contraindication to HRT. No fixed time limit. No strict age limit. If you're thriving on HRT , you can safely continue. Menopause care doesn't end at 60 , it evolves. Always review, personalize, and prioritize your health goals.